Question 8 1 / 1 point
Jamison has been prescribed citalopram (Celexa) to treat his depression. Education regarding how quickly selective serotonin reuptake inhibitor (SSRI) antidepressants work would be:
Appetite and concentration improve in the first 1 to 2 weeks.
Sleep should improve almost immediately upon starting citalopram.
Full response to the SSRI may take 2 to 4 months after he reaches the full therapeutic dose.
His dysphoric mood will improve in 1 to 2 weeks.
Question 9 1 / 1 point
Patients who have a poor metabolism phenotype will have:
Slowed metabolism of a prodrug into an active drug, leading to accumulation of Prodrug
Accumulation of inactive metabolites of drugs
A need for increased dosages of medications
Increased elimination of an active drug
Question 10 1 / 1 point
The drug of choice for type 2 diabetics is metformin. Metformin:
Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Increases intestinal uptake of glucose
Prevents weight gain associated with hyperglycemia
Question 11 1 / 1 point
The first-line therapy for mild-persistent asthma is:
Low-dose inhaled corticosteroids
Question 12 1 / 1 point
All of the following statements about the Beer’s List are true except:
It is a list of medications or medication classes that should generally be avoided in persons 65 years or older because they are either ineffective or they pose unnecessarily high risk for older persons and a safer alternative is available.
It is derived from the expert opinion of one geriatrician and is not evidence-based.
These criteria have been adopted by the Centers for Medicare and Medicaid Services for regulation of long-term care facilities.
These criteria are directed at the general population of patients over 65 years of age and do not take disease states into consideration.
Question 13 1 / 1 point
It is a long-acting drug with potential for toxicity.
Nitrate tolerance can develop.
Orthostatic hypotension is a common adverse effect.
It must be taken with milk or food.
Question 14 1 / 1 point
True contraindications to diphtheria, tetanus, and acellular pertussis (DTaP or Tdap) vaccine include:
Fever up to 104oF (40.5oC) after previous DTaP vaccine
Family history of seizures after DTaP vaccine
Anaphylactic reaction with a previous dose
Question 15 1 / 1 point
Gender differences between men and women in pharmacokinetics include:
More rapid gastric emptying so that drugs absorbed in the stomach have less exposure to absorption sites
Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of distribution
Increased levels of bile acids so that drugs metabolized in the intestine have higher concentrations
Slower organ blood flow rates so drugs tend to take longer to be excreted